医药卫生

作品数:13350591被引量:8260778H指数:438
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相关作者:胡大一王伟李静李莉张伟更多>>
相关机构:复旦大学中国人民解放军总医院华中科技大学同济医学院山东大学更多>>
发文主题:护理疗效观察疗效儿童糖尿病更多>>
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发文基金:国家自然科学基金国家重点基础研究发展计划国家科技重大专项国家科技支撑计划更多>>
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From regenerative strategies to pharmacological approaches:can we fine-tune treatment for Parkinson's disease?
《中国神经再生研究:英文版》2022年第5期933-936,共4页Rita Caridade Silva Helena Sofia Domingues António J.Salgado Fábio G.Teixeira 
the financial support from Prémios Santa Casa Neurociências Prize Mantero Belard for Neurodegenerative Diseases Research(MB-28-2019);supported by the European Regional Development Fund(FEDER);through the Competitiveness Internationalization Operational Programme(POCI);by National funds;through the Foundation for Science and Technology(FCT);under the scope of projects UIDB/50026/2020;UIDP/50026/2020 and POCI-01-0145-FEDER-029751;developed under the scope of the project NORTE-01-0145-FEDER-000023;supported by the Northern Portugal Regional Operational Programme(NORTE 2020);under the Portugal 2020 Partnership Agreement,through the European Regional Development Fund(FEDER);funded by ICVS Scientific Microscopy Platform,member of the national infrastructure PPBI-Portuguese Platform of Bioimaging(PPBI-POCI-01-0145-FEDER-022122)(to FGT)。
Parkinson's disease is the second most prevalent neurodegenerative disorder worldwide.Clinically,it is characterized by severe motor complications caused by progressive degeneration of dopaminergic neurons.Current tre...
关键词:disease-modifying strategies mesenchymal stem cells N-ACETYLCYSTEINE neuroprotection Parkinson's disease stem cells secretome 
Embolic stroke of undetermined source:identification of patient subgroups for oral anticoagulation treatment
《中国神经再生研究:英文版》2022年第5期1005-1006,共2页Isabell Greeve Wolf-Rüdiger Schäbitz 
Background:Embolic stroke of undetermined source(ESUS),a subtype of cryptogenic stroke,was defined as acute ischemic stroke displaying an embolic or non-lacunar brain infarct pattern on imaging without significant ext...
关键词:al. ACUTE STENOSIS 
Gut-brain axis in traumatic brain injury: impact on neuroinflammation
《中国神经再生研究:英文版》2022年第5期1007-1008,共2页Marta Celorrio Stuart H.Friess 
supported by NIH R01-NS097721。
The gastrointestinal track is inhabited by tens of trillions of microorganisms. The gut microbiota is involved in gut motility, nutrient absorption and synthesis of metabolites that influence hmeostasis, metabolism an...
关键词:METABOLISM inflammation STASIS 
HOXA11-AS aggravates microglia-induced neuroinflammation after traumatic brain injury
《中国神经再生研究:英文版》2022年第5期1096-1105,共10页Xiang-Long Li Bin Wang Fu-Bing Yang Li-Gang Chen Jian You 
supported by the Science and Technology Project of Sichuan Province of China,No.2020YJ0188;the Science and Technology Foundation of Luzhou of China,No.2017LZXNYD-J10(both to XLL)。
Long noncoding RNAs(lnc RNAs)participate in many pathophysiological processes after traumatic brain injury by mediating neuroinflammation and apoptosis.Homeobox A11 antisense RNA(HOXA11-AS)is a member of the lnc RNA f...
关键词:astrocyte competitive endogenous RNA HOXA11-AS MICROGLIA MIDKINE miR-124-3p NEUROINFLAMMATION traumatic brain injury 
Chitin scaffold combined with autologous small nerve repairs sciatic nerve defects
《中国神经再生研究:英文版》2022年第5期1106-1114,共9页Bo Wang Chang-Feng Lu Zhong-Yang Liu Shuai Han Pi Wei Dian-Ying Zhang Yu-Hui Kou Bao-Guo Jiang 
supported by the National Natural Science Foundation of China,Nos.31571236(to YHK),81971177(to BGJ);Key Laboratory of Trauma and Neural Regeneration(Peking University)of the Ministry of Education of China,No.BMU2020XY005-03(to BGJ);the National Key Research and Development Program of China,No.2016YFC1101604(to DYZ);the Ministry of Education Innovation Program of China,No.IRT_16R01(to BGJ);China Postdoctoral Science Foundation-Funded Project,No.2019M664007(to ZYL)。
Although autologous nerve transplantation is the gold standard for treating peripheral nerve defects,it has many clinical limitations.As an alternative,various tissue-engineered nerve grafts have been developed to sub...
关键词:autologous small nerve chitin scaffold nerve defect nervous system peripheral nerve injury peripheral nerve regeneration sciatic nerve TRAUMA 
Correlations between hippocampal functional connectivity,structural changes,and clinical data in patients with relapsing-remitting multiple sclerosis:a case-control study using multimodal magnetic resonance imaging
《中国神经再生研究:英文版》2022年第5期1115-1124,共10页Xin-Quan Gu Ying Liu Jie-Bing Gu Lin-Fang Li Ling-Ling Fu Xue-Mei Han 
supported by the Project of International Cooperation of Jilin Province in China,No.20180414062GH(to XMH);Health research talents Project of Jilin Province in China,No.2019sc2018(to XMH)。
Multiple sclerosis is associated with structural and functional brain alterations leading to cognitive impairments across multiple domains including attention,memory,and the speed of information processing.The hippoca...
关键词:cognitive impairment diffusion tensor imaging fractional anisotropy functional connectivity functional magnetic resonance imaging hippocampus local consistency low frequency oscillation amplitude mean diffusivity multiple sclerosis NEURODEGENERATION 
Facial reanimation with interposition nerve graft or masseter nerve transfer:a comparative retrospective study
《中国神经再生研究:英文版》2022年第5期1125-1130,共6页Wen-Jin Wang Wei-Dong Zhu Mathias Tremp Gang Chen Zhao-Yan Wang Hao Wu Wei Wang 
supported by Shanghai Municipal Commission of Health and Family Planning Program,China,No.201504253(to WW);Special Fund for Science and Technology Innovation by Shanghai Jiao Tong University,China,No.YG2016MS10(to WW);the National Natural Science Foundation of China,Nos.81570906(to HW)and 81371086(to ZYW)。
Both interposition nerve grafts and masseter nerve transfers have been successfully used for facial reanimation after irreversible injuries to the cranial portion of the facial nerve.However,no comparative study of th...
关键词:facial palsy facial reanimation facial symmetry House-Brackmann score INTERPOSITION masseter nerve nerve graft oral commissure excursion resting symmetry SYNKINESIS 
Angiotensin-(1–7)reducesα-synuclein aggregation by enhancing autophagic activity in Parkinson's disease
《中国神经再生研究:英文版》2022年第5期1138-1145,共8页Qing Gao Rui Chen Liang Wu Qing Huang Xi-Xi Wang You-Yong Tian Ying-Dong Zhang 
supported by the National Natural Science Foundation of China,No.81801263(to QG)。
Abnormal accumulation ofα-synuclein contributes to the formation of Lewy bodies in the substantia nigra,which is considered the typical pathological hallmark of Parkinson's disease.Recent research indicates that angi...
关键词:Α-SYNUCLEIN apoptosis AUTOPHAGY dopaminergic neuron Lewy bodies neurodegenerative diseases Parkinson's disease renin-angiotensin system ROTENONE substantia nigra 
Biomimetic chitosan scaffolds with long-term controlled release of nerve growth factor repairs 20-mm-long sciatic nerve defects in rats
《中国神经再生研究:英文版》2022年第5期1146-1155,共10页Fa-Dong Liu Hong-Mei Duan Fei Hao Wen Zhao Yu-Dan Gao Peng Hao Zhao-Yang Yang Xiao-Guang Li 
supported by the National Natural Science Foundation of China,Nos.31900749(to PH),31730030(to XGL),81941011(to XGL),31971279(to ZYY),31771053(to HMD);the Natural Science Foundation of Beijing of China,No.7214301(to FH)。
Although autogenous nerve transplantation is the gold standard for treating peripheral nerve defects of considerable length,it still has some shortcomings,such as insufficient donors and secondary injury.Composite chi...
关键词:AXON CHITOSAN functional recovery myelin sheath nerve growth factor peripheral nerve injury pseudorabies virus regeneration SCAFFOLD sciatic nerve 
Antipsychotics preserve telomere length in peripheral blood mononuclear cells after acute oxidative stress injury
《中国神经再生研究:英文版》2022年第5期1156-1160,共5页Gabriel B.Polho Giancarlo M.Cardillo Daniel S.Kerr Thais Chile Wagner F.Gattaz Orestes V.Forlenza Helena P.Brentani Vanessa J.De-Paula 
supported by grants from FAPESP(Fundacao de AmparoàPesquisa de Sao Paulo,Grant no 2016/01302-9 and 2014/27129-6);CAPES(Coordenacao de Aperfeicoamento de Pessoal de Nível Superior)88887.463672/2019-00。
Antipsychotics may prolong or retain telomere length,affect mitochondrial function,and then affect the metabolism of nerve cells.To validate the hypothesis that antipsychotics can prolong telomere length after oxidati...
关键词:ANTIPSYCHOTIC ARIPIPRAZOLE cell culture CLOZAPINE HALOPERIDOL oxidative stress peripheral blood mononuclear cell telomere length 
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