医药卫生—肿瘤

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相关作者:吴孟超李建勇单保恩汤钊猷周晓军更多>>
相关机构:复旦大学中国医科大学山东大学第二军医大学更多>>
发文主题:乳腺癌肿瘤胃癌预后肺癌更多>>
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发文基金:国家自然科学基金广东省自然科学基金国家重点基础研究发展计划广东省科技计划工业攻关项目更多>>
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Potential effects of mesenchymal stem cell derived extracellular vesicles and exosomal miRNAs in neurological disorders
《中国神经再生研究:英文版》2021年第12期2359-2366,共8页Masako Nakano Mineko Fujimiya 
Mesenchymal stem cells are multipotent cells that possess anti-inflammatory,antiapoptotic and immunomodulatory properties.The effects of existing drugs for neurodegenerative disorders such as Alzheimer’s disease are ...
关键词:EXOSOMES extracellular vesicles mesenchymal stem cells MICRORNA neurological disorders 
Exploring genes that control microglial heterogeneity and transition
《中国神经再生研究:英文版》2021年第12期2397-2398,共2页Tomomi Okajima Fuminori Tsuruta 
Microglia,which comprise approximately 10%of total cells in the brain,are the resident immune cells in the central nervous system and contribute to maintaining the brain homeostasis through monitoring their microenvir...
关键词:al. HOMEOSTASIS transition 
The antiaging role of oxytocin
《中国神经再生研究:英文版》2021年第12期2413-2414,共2页Tarek Benameur Maria A.Panaro Chiara Porro 
The human life expectancy is continuously rising.In the past two decades,a large number of studies have been extensively exploring the molecular mechanisms which play critical roles in determining longevity.Aging is a...
关键词:AGING continuously PHYSIOLOGICAL 
Antrodia Cinnamomea ameliorates neointimal formation by inhibiting infl ammatory cell infi ltration through downregulation of adhesion molecule expression in vitro and in vivo
《食品科学与人类健康》2021年第4期421-430,共10页Yan Zhang Aijin Ma Hao Xi Ning Chen Rong Wang Chenhui Yang Jinbang Chen Pin Lü Fuping Zheng Wenyi Kang 
This work was supported by the National Key Research Project of China(2019YFC1606400);Major Public Welfare Projects in Henan Province(201300110200);National Key Research Project of Hebei Province(20375502D);Natural Science Foundation of Hebei Province(H2019206212);High-level Talent Funding Project of Hebei Province(A201905006);Fund of National R&D Center for Edible Fungus Processing Technology,Henan University(20200109);the Open Fund from Beijing Advanced Innovation Center for Food Nutrition and Human Health(20182025).
The increased vascular infl ammation is a key event in the development of atherosclerotic lesions.Antrodia cinnamomea has been shown to promote anticancerogenic activity through decreasing infl ammation.However,the po...
关键词:Antrodia cinnamomea Vascular smooth muscle cells Infl ammation Adhesion molecule Neointimal hyperplasia 
Multiple sclerosis:why we should focus on both sides of the(auto)antibody
《中国神经再生研究:英文版》2021年第12期2422-2424,共3页Jeroen den Dunnen Lynn Mes Willianne Hoepel Joost Smolders 
Various clinical and experimental findings suggest a pathogenic role of antibodies in multiple sclerosis(MS).Yet,whether antibodies contribute to the pathogenesis or progression of MS is still a subject of intense deb...
关键词:SCLEROSIS ANTIBODIES clinical 
Anti-colon cancer activity of water-soluble polysaccharides extracted from Gloeostereum incarnatum via Wnt/β-catenin signaling pathway
《食品科学与人类健康》2021年第4期460-470,共11页Jiawei He Anhui Yang Xuyu Zhao Yang Liu Shuyan Liu Di Wang 
This work was supported by the Ministry of Science and Technology of the People’s Republic of China(Grant No.2018YFE0107800);the“13th Five-year”Science and Technology Projects from Education Department in Jilin Province of P.R.China(Grant No.JJKH20190108KJ);Industrial Technology Research and Development Projects from Development and Reform Commission of Jilin Province(Grant No.2019C050-8).
The incidence rate of colon cancer ranks the third among malignant tumors worldwide.Gloeostereum incarnatum(GI),a fungus with homology of medicine and food,has multiple pharmacological activities.It was investigated i...
关键词:Gloeostereum incarnatum Water-soluble polysaccharides Colon cancer WNT/Β-CATENIN 
The normal cell proliferation and wound healing effect of polysaccharides from Ganoderma amboinense
《食品科学与人类健康》2021年第4期508-513,共6页Shuangzhi Zhao Ming Lei Hui Xu Hailun He Alexander Suvorov Junhua Wang Jiying Qiu Qingxin Zhou Jinyu Yang Leilei Chen 
This research was supported by the National Key Research and Development Program of China(2017YFC1601400);Shandong Provincial Key Research and Development Program(2019GHZ022);Taishan Scholar Program of Shandong Province(tsqn201909168);“Double Hundred”Program for Foreign Experts of Shandong Province(WST2017004).
To study the cell proliferation and wound healing activity of polysaccharides from Ganoderma amboinense(GAMPS),the polysaccharide was extracted by water extraction and alcohol precipitation method,and its monosacchari...
关键词:Ganoderma amboinense mycelium polysaccharide Proliferation promotion Wound healing Antioxidant activity 
Altered microRNA expression in animal models of Huntington’s disease and potential therapeutic strategies
《中国神经再生研究:英文版》2021年第11期2159-2169,共11页Bridget Martinez Philip V.Peplow 
A review of recent animal models of Huntington’s disease showed many microRNAs had altered expression levels in the striatum and cerebral cortex,and which were mostly downregulated.Among the altered microRNAs were mi...
关键词:animal model cerebral cortex HUNTINGTIN Huntington’s disease microRNA NEURODEGENERATION STRIATUM therapeutic strategies 
Mesenchymal stem cell treatment for peripheral nerve injury:a narrative review
《中国神经再生研究:英文版》2021年第11期2170-2176,共7页Rui-Cheng Zhang Wen-Qi Du Jing-Yuan Zhang Shao-Xia Yu Fang-Zhi Lu Hong-Mei Ding Yan-Bo Cheng Chao Ren De-Qin Geng 
funded by Clinical Medicine Key Project from the Social Development and Collaborative Innovation Plans in Xuzhou City of China,No.KC14SX016(to DQG).
Peripheral nerve injuries occur as the result of sudden trauma and lead to reduced quality of life.The peripheral nervous system has an inherent capability to regenerate axons.However,peripheral nerve regeneration fol...
关键词:axonal regeneration EXOSOMES genetic engineering mesenchymal stem cells neural conduit peripheral nerve peripheral nerve injury peripheral nerve regeneration Schwann cells sudden trauma 
Neuroimmune connections between corticotropinreleasing hormone and mast cells:novel strategies for the treatment of neurodegenerative diseases
《中国神经再生研究:英文版》2021年第11期2184-2197,共14页Piplu Bhuiyan Yi-Wei Wang Huan-Huan Sha Hong-Quan Dong Yan-Ning Qian 
supported by the National Natural Science Foundation of China,Nos.81671387(to YNQ),81701375(to HQD);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD),China.
Corticotropin-releasing hormone is a critical component of the hypothalamic–pituitary–adrenal axis,which plays a major role in the body’s immune response to stress.Mast cells are both sensors and effectors in the i...
关键词:blood-brain barrier corticotropin-releasing hormone gastrointestinal tract INFLAMMATORY mast cells NEUROIMMUNE neurological disorders 
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